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Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin
1. In the spontaneously hypertensive rat (SHR) and aging Wistar–Kyoto rats (WKY), acetylcholine releases an endothelium-derived contracting factor (EDCF) produced by endothelial cyclooxygenase-1, which stimulates thromboxane A(2) receptors (TP receptors) on vascular smooth muscle. The purpose of the...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751221/ https://ncbi.nlm.nih.gov/pubmed/16158068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706390 |
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