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Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin

1. In the spontaneously hypertensive rat (SHR) and aging Wistar–Kyoto rats (WKY), acetylcholine releases an endothelium-derived contracting factor (EDCF) produced by endothelial cyclooxygenase-1, which stimulates thromboxane A(2) receptors (TP receptors) on vascular smooth muscle. The purpose of the...

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Hlavní autoři: Gluais, Pascale, Lonchampt, Michel, Morrow, Jason D, Vanhoutte, Paul M, Feletou, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751221/
https://ncbi.nlm.nih.gov/pubmed/16158068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706390
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