Low concentrations of neuroactive steroids alter kinetics of [(3)H]ifenprodil binding to the NMDA receptor in rat frontal cortex

1. The modulatory effects of the two neurosteroids pregnenolone sulphate (PS) and pregnanolone sulphate (3α5βS) on [(3)H]ifenprodil binding to the N-methyl-D-aspartate (NMDA) receptor in rat frontal cortex were studied. 2. The binding for [(3)H]ifenprodil itself displayed monophasic kinetics in all...

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Hlavní autoři: Johansson, Tobias, Frändberg, Per-Anders, Nyberg, Fred, Le Grevès, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751215/
https://ncbi.nlm.nih.gov/pubmed/16170326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706397
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