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Pharmacokinetic/pharmacodynamic modelling of NSAIDs in a model of reversible inflammation in the cat

1. Data on the relationships between plasma concentration and analgesic and anti-inflammatory effects of NSAIDs are limited because most inflammation models do not permit pharmacokinetic/pharmacodynamic (PK/PD) modelling to be readily performed. 2. In this study, a kaolin-induced inflammation model...

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Detalhes bibliográficos
Main Authors: Giraudel, Jerome M, Diquelou, Armelle, Laroute, Valerie, Lees, Peter, Toutain, Pierre-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751204/
https://ncbi.nlm.nih.gov/pubmed/16113689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706372
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