Polarised Asymmetric Inheritance of Accumulated Protein Damage in Higher Eukaryotes

Disease-associated misfolded proteins or proteins damaged due to cellular stress are generally disposed via the cellular protein quality-control system. However, under saturating conditions, misfolded proteins will aggregate. In higher eukaryotes, these aggregates can be transported to accumulate in...

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Main Authors: Rujano, María A, Bosveld, Floris, Salomons, Florian A, Dijk, Freark, van Waarde, Maria A.W.H, van der Want, Johannes J.L, de Vos, Rob A.I, Brunt, Ewout R, Sibon, Ody C.M, Kampinga, Harm H
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2006
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1750924/
https://ncbi.nlm.nih.gov/pubmed/17147470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040417
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