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The first armadillo repeat is involved in the recognition and regulation of β-catenin phosphorylation by protein kinase CK1

Multiple phosphorylation of β-catenin by glycogen synthase kinase 3 (GSK3) in the Wnt pathway is primed by CK1 through phosphorylation of Ser-45, which lacks a typical CK1 canonical sequence. Synthetic peptides encompassing amino acids 38–64 of β-catenin are phosphorylated by CK1 on Ser-45 with low...

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Detalhes bibliográficos
Main Authors: Bustos, Victor H., Ferrarese, Anna, Venerando, Andrea, Marin, Oriano, Allende, Jorge E., Pinna, Lorenzo A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1750875/
https://ncbi.nlm.nih.gov/pubmed/17172446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609424104
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