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Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine
Furin plays a crucial role in embryogenesis and homeostasis and in diseases such as Alzheimer's disease, cancer, and viral and bacterial infections. Thus, inhibition of furin may provide a feasible and promising approach for therapeutic intervention of furin-mediated disease mechanisms. Here, w...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1750872/ https://ncbi.nlm.nih.gov/pubmed/17179036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606555104 |
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