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Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis.

In a rabbit model of Escherichia coli endocarditis, we studied the penetration into infected vegetations and the antibacterial effect of ceftriaxone. Ceftriaxone was given at different dosages, alone or with an interfering agent, diclofenac, a nonsteroidal anti-inflammatory drug, to determine the pr...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Joly, V, Pangon, B, Vallois, J M, Abel, L, Brion, N, Bure, A, Chau, N P, Contrepois, A, Carbon, C
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3324957/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1632
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