Ceftriaxone-sulbactam combination in rabbit endocarditis caused by a strain of Klebsiella pneumoniae producing extended-broad-spectrum TEM-3 beta-lactamase.

We studied the activity of the combination of sulbactam and ceftriaxone against a Klebsiella pneumoniae strain producing TEM-3, a new extended-broad-spectrum beta-lactamase, in an endocarditis model. In vitro, ceftriaxone was strongly inactivated in the presence of TEM-3 (MBC, 128 micrograms/ml with...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Caron, F, Gutmann, L, Bure, A, Pangon, B, Vallois, J M, Pechinot, A, Carbon, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2073099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.11.2070
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