Ceftriaxone-sulbactam combination in rabbit endocarditis caused by a strain of Klebsiella pneumoniae producing extended-broad-spectrum TEM-3 beta-lactamase.

We studied the activity of the combination of sulbactam and ceftriaxone against a Klebsiella pneumoniae strain producing TEM-3, a new extended-broad-spectrum beta-lactamase, in an endocarditis model. In vitro, ceftriaxone was strongly inactivated in the presence of TEM-3 (MBC, 128 micrograms/ml with...

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Hauptverfasser: Caron, F, Gutmann, L, Bure, A, Pangon, B, Vallois, J M, Pechinot, A, Carbon, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC172001/
https://ncbi.nlm.nih.gov/pubmed/2073099
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