Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis.

In a rabbit model of Escherichia coli endocarditis, we studied the penetration into infected vegetations and the antibacterial effect of ceftriaxone. Ceftriaxone was given at different dosages, alone or with an interfering agent, diclofenac, a nonsteroidal anti-inflammatory drug, to determine the pr...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Joly, V, Pangon, B, Vallois, J M, Abel, L, Brion, N, Bure, A, Chau, N P, Contrepois, A, Carbon, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3324957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1632
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