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Treatment of Clostridium difficile colitis in hamsters with a lipopeptide antibiotic, LY146032.

LY146032, an acidic lipopeptide antibiotic which inhibits the biosynthesis of cell wall peptidoglycan, was found to be effective in delaying death in a hamster model of pseudomembranous colitis. A dose of 0.05 mg/day was effective. The equivalent protection with vancomycin required a dose 100-fold h...

詳細記述

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書誌詳細
主要な著者: Dong, M Y, Chang, T W, Gorbach, S L
フォーマット: Artigo
言語:Inglês
出版事項: 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC174884/
https://ncbi.nlm.nih.gov/pubmed/2821892
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