Treatment of Clostridium difficile colitis in hamsters with a lipopeptide antibiotic, LY146032.
LY146032, an acidic lipopeptide antibiotic which inhibits the biosynthesis of cell wall peptidoglycan, was found to be effective in delaying death in a hamster model of pseudomembranous colitis. A dose of 0.05 mg/day was effective. The equivalent protection with vancomycin required a dose 100-fold h...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Antimicrob Agents Chemother |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
1987
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2821892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.7.1135 |
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