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Viral protease cleavage of inhibitor of κBα triggers host cell apoptosis

Apoptosis is an innate immune response to viral infection that limits viral replication. However, the mechanisms by which cells detect viral infection and activate apoptosis are not completely understood. We now show that during Coxsackievirus infection, the viral protease 3C(pro) cleaves inhibitor...

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Bibliografische gegevens
Hoofdauteurs: Zaragoza, Carlos, Saura, Marta, Padalko, Elizaveta Y., Lopez-Rivera, Ester, Lizarbe, Tania R., Lamas, Santiago, Lowenstein, Charles J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748175/
https://ncbi.nlm.nih.gov/pubmed/17138672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606019103
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