Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor

Epidermal growth factor receptor (EGFR) at membrane microdomains plays an essential role in the growth control of epidermal cells, including cancer cells derived therefrom. Ligand-dependent activation of EGFR tyrosine kinase is known to be inhibited by ganglioside GM3, but to a much lesser degree by...

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Detaylı Bibliyografya
Asıl Yazarlar: Yoon, Seon-Joo, Nakayama, Ken-ichi, Hikita, Toshiyuki, Handa, Kazuko, Hakomori, Sen-itiroh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748164/
https://ncbi.nlm.nih.gov/pubmed/17142315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609281103
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