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Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor

Epidermal growth factor receptor (EGFR) at membrane microdomains plays an essential role in the growth control of epidermal cells, including cancer cells derived therefrom. Ligand-dependent activation of EGFR tyrosine kinase is known to be inhibited by ganglioside GM3, but to a much lesser degree by...

詳細記述

保存先:
書誌詳細
主要な著者: Yoon, Seon-Joo, Nakayama, Ken-ichi, Hikita, Toshiyuki, Handa, Kazuko, Hakomori, Sen-itiroh
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748164/
https://ncbi.nlm.nih.gov/pubmed/17142315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609281103
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