Wird geladen...
α(1)-Antitrypsin deficiency • 4: Molecular pathophysiology
The molecular basis of α(1)-antitrypsin deficiency is reviewed and is shown to be due to the accumulation of mutant protein as ordered polymers within the endoplasmic reticulum of hepatocytes. The current goals are to determine the cellular response to polymeric α(1)-antitrypsin and to develop thera...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Group
2004
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1747018/ https://ncbi.nlm.nih.gov/pubmed/15170041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2003.006528 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|