טוען...
α(1)-Antitrypsin deficiency • 4: Molecular pathophysiology
The molecular basis of α(1)-antitrypsin deficiency is reviewed and is shown to be due to the accumulation of mutant protein as ordered polymers within the endoplasmic reticulum of hepatocytes. The current goals are to determine the cellular response to polymeric α(1)-antitrypsin and to develop thera...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMJ Group
2004
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1747018/ https://ncbi.nlm.nih.gov/pubmed/15170041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2003.006528 |
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