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Association of CCR5Δ32 with reduced risk of childhood but not adult asthma

Background: A number of potential candidate genes have been implicated in the pathogenesis of asthma. A 32 base pair deletion in the CCR5 gene renders this chemokine receptor non-functioning and has been shown to be associated with a reduced prevalence of asthma in childhood. The mechanism may be re...

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Hlavní autoři: Srivastava, P, Helms, P, Stewart, D, Main, M, Russell, G
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746589/
https://ncbi.nlm.nih.gov/pubmed/12612298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.3.222
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