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The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele
The Δ32 mutation at the CCR5 locus is a well-studied example of natural selection acting in humans. The mutation is found principally in Europe and western Asia, with higher frequencies generally in the north. Homozygous carriers of the Δ32 mutation are resistant to HIV-1 infection because the mutat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1255740/ https://ncbi.nlm.nih.gov/pubmed/16216086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030339 |
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