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The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele

The Δ32 mutation at the CCR5 locus is a well-studied example of natural selection acting in humans. The mutation is found principally in Europe and western Asia, with higher frequencies generally in the north. Homozygous carriers of the Δ32 mutation are resistant to HIV-1 infection because the mutat...

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Autori principali: Novembre, John, Galvani, Alison P, Slatkin, Montgomery
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1255740/
https://ncbi.nlm.nih.gov/pubmed/16216086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030339
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