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Evaluating plague and smallpox as historical selective pressures for the CCR5-Δ32 HIV-resistance allele
The high frequency, recent origin, and geographic distribution of the CCR5-Δ32 deletion allele together indicate that it has been intensely selected in Europe. Although the allele confers resistance against HIV-1, HIV has not existed in the human population long enough to account for this selective...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299980/ https://ncbi.nlm.nih.gov/pubmed/14645720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2435085100 |
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