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Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor

Background: Smooth muscle contraction is one of the hallmarks of asthma. A recently developed pyridine derivative, Y-27632, a selective Rho kinase inhibitor, has been reported to inhibit the smooth muscle contraction of human and animal trachea in ex vivo systems but its effect in animal models of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hashimoto, K, Peebles, R, Sheller, J, Jarzecka, K, Furlong, J, Mitchell, D, Hartert, T, Graham, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746359/
https://ncbi.nlm.nih.gov/pubmed/12037228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.57.6.524
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