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Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans.

A single-dose, oral Salmonella typhi vaccine strain has been sought as a carrier or vector of cloned genes encoding protective antigens of other pathogens. Such a hybrid vaccine, administered orally, would stimulate immune responses both at the mucosal surface and in the systemic compartment and wou...

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Dettagli Bibliografici
Autori principali: Tacket, C O, Sztein, M B, Losonsky, G A, Wasserman, S S, Nataro, J P, Edelman, R, Pickard, D, Dougan, G, Chatfield, S N, Levine, M M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC174616/
https://ncbi.nlm.nih.gov/pubmed/9009296
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