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Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans.

A single-dose, oral Salmonella typhi vaccine strain has been sought as a carrier or vector of cloned genes encoding protective antigens of other pathogens. Such a hybrid vaccine, administered orally, would stimulate immune responses both at the mucosal surface and in the systemic compartment and wou...

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Published in:Infect Immun
Main Authors: Tacket, C O, Sztein, M B, Losonsky, G A, Wasserman, S S, Nataro, J P, Edelman, R, Pickard, D, Dougan, G, Chatfield, S N, Levine, M M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.452-456.1997
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