Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis.

The direct binding of platelets by bacteria is a postulated central mechanism in the pathogenesis of endocarditis. To address the role of binding more definitively, we employed Tn551 insertional mutagenesis of Staphylococcus aureus parental strain ISP479 to generate an isogenic variant (strain PS12)...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	Sullam, P M, Bayer, A S, Foss, W M, Cheung, A L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8945526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.12.4915-4921.1996
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