Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis.

The direct binding of platelets by bacteria is a postulated central mechanism in the pathogenesis of endocarditis. To address the role of binding more definitively, we employed Tn551 insertional mutagenesis of Staphylococcus aureus parental strain ISP479 to generate an isogenic variant (strain PS12)...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Sullam, P M, Bayer, A S, Foss, W M, Cheung, A L
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1996
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8945526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.12.4915-4921.1996
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