Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis.

The direct binding of platelets by bacteria is a postulated central mechanism in the pathogenesis of endocarditis. To address the role of binding more definitively, we employed Tn551 insertional mutagenesis of Staphylococcus aureus parental strain ISP479 to generate an isogenic variant (strain PS12)...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Sullam, P M, Bayer, A S, Foss, W M, Cheung, A L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8945526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.12.4915-4921.1996
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