Tumor necrosis factor alpha and interleukin-12 contribute to resistance to the intracellular bacterium Brucella abortus by different mechanisms.

Both interleukin-12 (IL-12) and tumor necrosis factor alpha (TNF-alpha) are produced early in intracellular bacterial infection. Depletion of either IL-12 or TNF-alpha by a single injection of specific antibody 4 h before the injection of Brucella abortus 19 led to the exacerbation of infection 2 we...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Zhan, Y, Liu, Z, Cheers, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2782-2786.1996
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