Interleukin-10 downregulates protective immunity to Brucella abortus.

In vivo neutralization of interleukin-10 (IL-10) with an anti-IL-10 monoclonal antibody resulted in up to 10-fold fewer bacteria in the spleens of BALB/c mice infected with the virulent Brucella abortus strain 2308. In vitro neutralization of endogenous IL-10 in brucella antigen-stimulated cultures...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Fernandes, D M, Baldwin, C L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.3.1130-1133.1995
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