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Apolipoprotein E genotypes do not influence the age of onset in Huntington's disease

Objective: The ε4 allele of the apolipoprotein E (ApoE) gene has been defined as a critical factor for early onset neurodegeneration in Pick's, Parkinson's, and Alzheimer's disease. Unexpectedly, the ε4 allele appeared to delay the age of onset in Huntington's disease (HD) patien...

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Detalhes bibliográficos
Main Authors: Saft, C, Andrich, J, Brune, N, Gencik, M, Kraus, P, Przuntek, H, Epplen, J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1738834/
https://ncbi.nlm.nih.gov/pubmed/15548484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2003.022756
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