Failure to confirm influence of Methyltetrahydrofolate reductase (MTHFR) polymorphisms on age at onset of Huntington disease

BACKGROUND: Huntington disease (HD) is a fully penetrant, autosomal dominantly inherited disorder associated with abnormal expansions of a stretch of perfect CAG repeats in the 5' part of the IT15 gene. The number of repeat units is highly predictive for the age at onset (AO) of the disorder. B...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hansen, Wiebke, Saft, Carsten, Andrich, Jürgen, Müller, Thomas, Wieczorek, Stefan, Epplen, Jörg T, Arning, Larissa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327683/
https://ncbi.nlm.nih.gov/pubmed/16372906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-4-12
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge