No association between polymorphisms in the BDNF gene and age at onset in Huntington disease

BACKGROUND: Recent evidence suggests that brain-derived neurotrophic factor (BDNF) is an attractive candidate for modifying age at onset (AO) in Huntington disease (HD). In particular, the functional Val66Met polymorphism appeared to exert a significant effect. Here we evaluate BDNF variability with...

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Detalhes bibliográficos
Main Authors: Mai, Maren, Akkad, Amer D, Wieczorek, Stefan, Saft, Carsten, Andrich, Jürgen, Kraus, Peter H, Epplen, Jörg T, Arning, Larissa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637098/
https://ncbi.nlm.nih.gov/pubmed/17096834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-79
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