Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells.

Pseudomonas exotoxin A (PE) binds and enters mammalian cells via the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP). The toxin then requires proteolytic cleavage to generate an enzymatically active fragment with translocates to the cell cytosol and inhibits pro...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Gu, M, Gordon, V M, Fitzgerald, D J, Leppla, S H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550202/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.2.524-527.1996
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!