Proteolytic activation of tick-borne encephalitis virus by furin.

Flaviviruses are assembled intracellularly in an immature form containing heterodimers of two envelope proteins, E and prM. Shortly before the virion exits the cell, prM is cleaved by a cellular enzyme, and this processing step can be blocked by treatment with agents that raise the pH of exocytic co...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Stadler, K, Allison, S L, Schalich, J, Heinz, F X
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8475-8481.1997
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