Proteolytic activation of tick-borne encephalitis virus by furin.
Flaviviruses are assembled intracellularly in an immature form containing heterodimers of two envelope proteins, E and prM. Shortly before the virion exits the cell, prM is cleaved by a cellular enzyme, and this processing step can be blocked by treatment with agents that raise the pH of exocytic co...
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| Опубликовано в:: | J Virol |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8475-8481.1997 |
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