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Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment

Background: Hereditary non-polyposis colorectal cancer (HNPCC) is caused by germline mutations of mismatch repair genes, usually in hMLH1 or hMSH2. All earlier studies on penetrance except one population based study were conducted in HNPCC families and did not correct for the way in which these fami...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Quehenberger, F, Vasen, H, van Houwelingen, H C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Group 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736072/
https://ncbi.nlm.nih.gov/pubmed/15937084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.024299
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