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Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer

Background: The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. There is reduced expression of FAS but elevated expression of FASL in many types of human cancers includ...

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Main Authors: Zhang, X, Miao, X, Sun, T, Tan, W, Qu, S, Xiong, P, Zhou, Y, Lin, D
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736067/
https://ncbi.nlm.nih.gov/pubmed/15937082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.030106
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