Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer

Background: The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. There is reduced expression of FAS but elevated expression of FASL in many types of human cancers includ...

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Detalhes bibliográficos
Main Authors: Zhang, X, Miao, X, Sun, T, Tan, W, Qu, S, Xiong, P, Zhou, Y, Lin, D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2005
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736067/
https://ncbi.nlm.nih.gov/pubmed/15937082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.030106
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