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Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer
Background: The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. There is reduced expression of FAS but elevated expression of FASL in many types of human cancers includ...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Group
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1736067/ https://ncbi.nlm.nih.gov/pubmed/15937082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.030106 |
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