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A molecular investigation of true dominance in Huntington's disease

Huntington's disease (HD) is thought to show true dominance, since subjects with two mutant alleles have been reported to have similar ages at onset of disease compared to heterozygous sibs. We have investigated this phenomenon using a cell culture model. Protein aggregate formation was used as...

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Detalhes bibliográficos
Main Authors: Narain, Y., Wyttenbach, A., Rankin, J., Furlong, R., Rubinsztein, D.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734229/
https://ncbi.nlm.nih.gov/pubmed/10528852
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