Role of lipopolysaccharide (LPS), interleukin-1, interleukin-6, tumor necrosis factor, and dexamethasone in regulation of LPS-binding protein expression in normal hepatocytes and hepatocytes from LPS-treated rats.

Lipopolysaccharide (LPS)-binding protein (LBP) has been reported to be an acute-phase protein. LBP binds to LPS with a high affinity; LPS-LBP complexes then interact with the receptor CD14, resulting in increased expression of LPS-inducible genes. Hepatocytes represent a major source of LBP, but lit...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Wan, Y, Freeswick, P D, Khemlani, L S, Kispert, P H, Wang, S C, Su, G L, Billiar, T R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7790054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.7.2435-2442.1995
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