The Internalization Time Course of a Given Lipopolysaccharide Chemotype Does Not Correspond to Its Activation Kinetics in Monocytes

The prerequisites for the initiation of pathophysiological effects of endotoxin (lipopolysaccharide [LPS]) include binding to and possibly internalization by target cells. Monocytes/macrophages are prominent target cells which are activated by LPS to release various pro- and anti-inflammatory mediat...

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Main Authors: Lentschat, A., El-Samalouti, V. T., Schletter, J., Kusumoto, S., Brade, L., Rietschel, E. T., Gerdes, J., Ernst, M., Flad, H.-D., Ulmer, A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115998/
https://ncbi.nlm.nih.gov/pubmed/10225915
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