Diphosphoryl lipid A from Rhodobacter sphaeroides inhibits complexes that form in vitro between lipopolysaccharide (LPS)-binding protein, soluble CD14, and spectrally pure LPS.

An early event in septic shock is the activation of macrophages by a complex consisting of lipopolysaccharide (LPS), LPS-binding protein (LBP), and the cell surface antigen CD14. The complexes that form between [3H]ReLPS (ReLPS is deep-rough-chemotype hexacyl LPS from E. coli D31m4), soluble CD14 (s...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Jarvis, B W, Lichenstein, H, Qureshi, N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.8.3011-3016.1997
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