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Frataxin activates mitochondrial energy conversion and oxidative phosphorylation

Friedreich's ataxia (FA) is an autosomal recessive disease caused by decreased expression of the mitochondrial protein frataxin. The biological function of frataxin is unclear. The homologue of frataxin in yeast, YFH1, is required for cellular respiration and was suggested to regulate mitochond...

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Detalhes bibliográficos
Main Authors: Ristow, Michael, Pfister, Markus F., Yee, Andrew J., Schubert, Markus, Michael, Laura, Zhang, Chen-Yu, Ueki, Kojhiro, Michael, M. Dodson, Lowell, Bradford B., Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17325/
https://ncbi.nlm.nih.gov/pubmed/11035806
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