Oral vaccination with an attenuated Salmonella typhimurium strain expressing Borrelia burgdorferi OspA prevents murine Lyme borreliosis.

Borrelia burgdorferi is the causative agent of Lyme disease. In the mouse model, protection is correlated with the development of antibodies to a major outer surface protein, OspA. In this study, we expressed OspA in an attenuated strain of Salmonella typhimurium and tested the efficacy of the trans...

Full description

Bibliographic Details

Published in:	Infect Immun
Main Authors:	Dunne, M, al-Ramadi, B K, Barthold, S W, Flavell, R A, Fikrig, E
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7890431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.4.1611-1614.1995
Tags:	Add Tag No Tags, Be the first to tag this record!