Oral vaccination with an attenuated Salmonella typhimurium strain expressing Borrelia burgdorferi OspA prevents murine Lyme borreliosis.

Borrelia burgdorferi is the causative agent of Lyme disease. In the mouse model, protection is correlated with the development of antibodies to a major outer surface protein, OspA. In this study, we expressed OspA in an attenuated strain of Salmonella typhimurium and tested the efficacy of the trans...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Dunne, M, al-Ramadi, B K, Barthold, S W, Flavell, R A, Fikrig, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7890431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.4.1611-1614.1995
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