Oral vaccination with an attenuated Salmonella typhimurium strain expressing Borrelia burgdorferi OspA prevents murine Lyme borreliosis.

Borrelia burgdorferi is the causative agent of Lyme disease. In the mouse model, protection is correlated with the development of antibodies to a major outer surface protein, OspA. In this study, we expressed OspA in an attenuated strain of Salmonella typhimurium and tested the efficacy of the trans...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Dunne, M, al-Ramadi, B K, Barthold, S W, Flavell, R A, Fikrig, E
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1995
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7890431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.4.1611-1614.1995
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