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Presence of mitochondrial tRNA (Leu(UUR)) A to G 3243 mutation in DNA extracted from serum and plasma of patients with type 2 diabetes mellitus

Aims/Background—An A to G substitution at base pair 3243 in the mitochondrial tRNA (Leu(UUR)) gene (mt3243) is commonly associated with maternally inherited diabetes and deafness, and other diseases. It is possible that cell free mitochondrial DNA exists in serum and plasma from these patients, and...

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Main Authors: Zhong, S., Ng, M., Lo, Y, Chan, J., Johnson, P.
格式: Artigo
語言:Inglês
出版: 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1731206/
https://ncbi.nlm.nih.gov/pubmed/10911806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.53.6.466
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