Nonglassy kinetics in the folding of a simple single-domain protein
Theory suggests that the otherwise rapid folding of simple heteropolymer models becomes “glassy”—dominated by multiple kinetically trapped misfolded states—at low temperatures or when the overall bias toward the native state is reduced relative to the depth of local minima. Experimental observations...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.22.12014 |
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