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Mass spectrometry and immobilized enzymes for the screening of inhibitor libraries

A technique has been developed to rapidly screen enzyme inhibitor candidates from complex mixtures, such as those created by combinatorial synthesis. Inhibitor libraries are screened by using immobilized enzyme technologies and electrospray ionization ion cyclotron resonance mass spectrometry. The l...

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Bibliografische gegevens
Hoofdauteurs: Cancilla, Mark T., Leavell, Michael D., Chow, Jason, Leary, Julie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17285/
https://ncbi.nlm.nih.gov/pubmed/11035807
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