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High-Throughput Screening of Small Molecule Libraries using SAMDI Mass Spectrometry

[Image: see text] High-throughput screening is a common strategy used to identify compounds that modulate biochemical activities, but many approaches depend on cumbersome fluorescent reporters or antibodies and often produce false-positive hits. The development of “label-free” assays addresses many...

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Detalhes bibliográficos
Main Authors: Gurard-Levin, Zachary A., Scholle, Michael D., Eisenberg, Adam H., Mrksich, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132997/
https://ncbi.nlm.nih.gov/pubmed/21639106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co2000373
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