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Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists
BACKGROUND—The vasoactive peptide endothelin 1 (ET-1) acts via two receptors, endothelin receptors A (ET(A)) and B (ET(B)). ET-1 is overexpressed by human cancers in vivo and in vitro and may be mitogenic for cancer cells. METHOD—To elucidate if ET-1 is a growth regulator the following were investig...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1728110/ https://ncbi.nlm.nih.gov/pubmed/11034585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.5.685 |
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